By F. Robert Brush
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Additional resources for Psychoendocrinology
There is no evidence for coordinated central and peripheral activation of P~endorphin-containing systems as yet; the existence of an effective barrier between them may ensure that their operations remain secluded from each other (Barna et al, 1988). A second member of this family of peptides, ACTH, is also excluded from the CSF. Studies in monkeys have shown that ACTH (1-24) given systemically is not detected in the CSF, though serum levels increased fourfold. The serum levels of ACTH in the untreated, adrenalectomized monkey reach about 10 times their normal values; yet ACTH in the CSF does not increase (Fig.
Matsui, K . , Iitake, K . , Shoji, M . , Inoue, M . , and Yoshinaga, K . (1988). Effects o f hemorrhage on vasopressin and Met-Enk releases in blood and cerebrospinal fluid in dogs. Am. J. Physiol. 255, R731-736. Pardridge, W. M . , and Meitus, C . J . (1979)- Transport o f steroid hormones through the blood-brain barrier. / . Clin. Invest. 64, 145-154. Pederson, C . , and Prange, A. J . (1979). Induction o f maternal behavior in virgin female rats after intracerebroventricular administration o f oxytocin.
Concentration o f E 2 receptors in selected nuclei and subregions. Results are expressed as femtomoles per milligram o f E 2 specifically bound per milligram o f protein (fm E 2 / m g P). The abbreviations used are P V P O A , periventricular preoptic area; M P O A , medial preoptic area; P V A H , periventricular anterior hypothalamus; S C P O A , suprachiasmatic preoptic nucleus; A R C - M E , arcuate nucleusmedian eminence; V M N , ventromedial nucleus; M A , medial amygdaloid nucleus; S O , supraoptic nucleus; P V N , paraventricular nucleus; N s T , bed nucleus o f the stria terminalis; V P N , ventral premammillary nucleus; D M N , dorsomedial nucleus; D G , dentate gyrus; D B , nucleus of the diagonal band of Broca; O T , olfactory tubercle; L S , lateral septum.
Psychoendocrinology by F. Robert Brush