By K. Suda
The pancreas is an unobtrusive organ, and the customers and chances of fixing the physiological and pathological nature of its habit are a number of. while carrying out a pathological examine or an research of the pancreas, it is very important reflect on its anatomical and embryological foundation in addition to the prevalence of age-related common lesions. in regards to the latter, either mucous mobile hyperplasia and the cystic dilatation of the department pancreatic duct lead to the amendment of the tissue surrounding it, i.e. atrophy. in addition, pathological adjustments within the pancreas are focal or patchy in nature, specially in non-tumorous lesions, and are on the topic of its neighboring or adjoining organs. according to the event and information of its members, this book describes intimately a variety of pathological alterations within the habit of the pancreas. Pathologists, physicians and surgeons who're attracted to the pancreas will locate it an invaluable reference resource either for his or her day-by-day paintings in addition to for destiny study.
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Extra info for Pancreas - Pathological Practice and Research
So-called dorsal pancreatitis in patients with pancreas divisum. Tissue of the ventral pancreas did not show any abnormal findings (a), whereas the dorsal pancreas tissue demonstrated marked atrophy or disappearance of acinar cells and inter- and intralobular fibrosis (b). HE stain. ϫ100 (a), ϫ100 (b). Branch Duct Fusion of the Ventral and Dorsal Pancreatic Duct A case of fusion via two so-called inferior branches between the ventral and dorsal pancreatic ducts was studied both macroscopically and immunohistochemically, based on the organogenesis of the pancreas , as shown in figure 11.
Glands can be immunostained with cytokeratin 7 and MUC5AC, markers of pancreaticobiliary phenotype and gastric surface mucin, respectively (fig. 7). Hence, such glands maintain the pancreaticobiliary phenotype, although they are situated on inside or toward the duodenal lumen, and acquire a selectively gastric surface phenotype. 064) as shown in table 2. However, in 2 cases the distended glands showed a high proliferation index (fig. 5c) and were identified with adenomatous or adenoma-like structures admixed with or without similar proliferation in the tips of the valvules.
Anat Rec 1910;4:297–304. Ghon A, Roman B: Ein Fall von Missbildung des Pankreas mit Diabetes mellitus. Prog Med Wochenschr Nr 1913;38:524–526. Suda K, Matsumoto Y, Fujii H, et al: Clinicopathologic differentiation of atrophy of the pancreatic body and tail aplasia. Int J Pancreatol 1998;24:227–235. Suda K, Miyano T, Suzuki F, et al: Clinicopathologic and experimental studies on cases of abnormal pancreatico-choledocho-ductal junction. Acta Pathol Jpn 1987;37:1549–1562. Matsumoto Y, Itakura J, Matsuda M, et al: Diagnosis of anomalies of the pancreas by pancreatography.
Pancreas - Pathological Practice and Research by K. Suda