By R. B. Page (auth.), Dr. Detlev Ganten M.D., Ph.D., Dr. Donald Pfaff Ph.D. (eds.)
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Additional info for Morphology of Hypothalamus and Its Connections
Large animals are required, as the neurohypophyseal sample must be of sufficient size to contain at least 400 micro spheres in order to assure accurate and reproducible measurements (Buckberg et al. 1971). This method allows determination of regional cerebral and regional neurohypophyseal blood flow, but not of adenohypophyseal blood flow. The absence of a direct arterial supply and the presence of a vascular supply through portal vessels prohibits the application of the technique to the determination of adenohypophyseal blood flow.
1984). Hence, measurement of glucose metabolism will not provide an accurate measure of total energy expenditure. The neurohypophysis is made up of axon terminals whose associated cell bodies lie behind the blood-brain barrier in the hypothalamus and (presumably) consume glucose as their major fuel. One is thus faced with the situation that mitochondria in the cell body behind the bloodbrain barrier metabolize glucose to CO 2 and H 2 0 to obtain ATP and hence energy to accomplish protein hormone synthesis, whereas the mitochondria in the terminal of the same cell (lying outside the blood-brain barrier) do not perform this task.
8 Summary and Conclusions The pituitary portal system develops from mesenchyme entrapped between the advancing evaginations of the stomodeum and the floor of the diencephalon. It is comprised of feeding arteries (the inferior, middle, and superior hypophyseal arteries), the neurohypophyseal capillary bed, portal vessels which pass from the neurohypophysis and adenohypophysis, the adenohypophyseal capillary bed, and draining veins - the inferior hypophyseal veins. A single capillary bed extends throughout the neurohypophysis: the median eminence, the infundibular stem, and the neural lobe.
Morphology of Hypothalamus and Its Connections by R. B. Page (auth.), Dr. Detlev Ganten M.D., Ph.D., Dr. Donald Pfaff Ph.D. (eds.)