By Donald William Robert McKinley
Данная книга является классической монографией по метеорным исследованиям канадского учёного Дональда МакКинли, основанная на программе исследований 50-60-х гг. ХХ в. Национального Исследовательского Совета Канады, г. Оттава. В основу монографии легли исследования по визуальному, фотографическому и радионаблюдению метеоров.
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A rational optimization approach includes that the main parameters affecting the overall ET pathway and hence the ﬁnal sensor response have to be investigated in order to ﬁnd reasonable tools for tuning the performance of the selected biosensor design. As a matter of fact, it is well known that it is impossible to keep parameters constant while changing others. , may be altered simultaneously. Thus, a “pseudo” rational approach has to be complemented by combinatorial approaches in which the overall parameter space is addressed by means of a large number of measurements after permutation of all possible inﬂuencing parameters.
The properties of a hydrogel may also provide an enzyme-friendly microenvironment, and even extend the lifetime of the involved biological recognition elements. Electron hopping between redox relays covalently incorporated at the polymer backbone dominates the ET. Note, however, that often the ﬁrst ET between the active site of the redox enzyme and the polymer-bound redox relay represents the rate-limiting step of the entire ET reaction. Biosensors have been miniaturized on the basis of redox hydrogels by employing manual dropping or dipping procedures and, for example, needle-type implantable glucose sensors have been fabricated [137, 286–289].
2 Criteria for “Good” Biosensor Research a single-use device differ from those for multi-analysis and continuous monitoring and have to be taken into account when considering overall biosensor architecture. 2 Criteria for “Good” Biosensor Research It is obvious that science does not always lead to ground-breaking advancements that are worth publishing. This is also very much true for publications from biosensor-related research. The area of biosensor research is even more susceptible to publications that do not signiﬁcantly contribute to the present state of the art, since the basic equipment for doing high-level biosensor research is comparatively cheap.
Meteor science and engineering by Donald William Robert McKinley