Get Knobil and Neill's Physiology of Reproduction, Volume 1-2, PDF

By Paul Wassarman, Jimmy D. Neill

ISBN-10: 0125154003

ISBN-13: 9780125154000

The third version, the 1st new one in ten years, comprises assurance of molecular degrees of element bobbing up from the final decade's explosion of knowledge at this point of organismic association. There are five new affiliate Editors and approximately 2/3 of the chapters have new authors. Chapters ready by way of go back authors are generally revised. a number of new chapters were extra relating to being pregnant, reflecting the lively research of this subject over the past decade.The info coated comprises either human and experimental animals; easy principels are sought, and knowledge on the organismic and molecular degrees are awarded. *The best accomplished paintings at the body structure of reproduction*Edited and authored by way of the world's prime scientists within the field*Is a synthesis of the molecular, mobile, and organismic degrees of organization*Bibliogrpahics of chapters are vast and canopy all of the suitable literature

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Download PDF by Paul Wassarman, Jimmy D. Neill: Knobil and Neill's Physiology of Reproduction, Volume 1-2,

The third version, the 1st new one in ten years, comprises assurance of molecular degrees of element bobbing up from the final decade's explosion of knowledge at this point of organismic association. There are five new affiliate Editors and approximately 2/3 of the chapters have new authors. Chapters ready via go back authors are generally revised.

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Extra resources for Knobil and Neill's Physiology of Reproduction, Volume 1-2, Third Edition

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It is suggested that the outer dense fibers provide added strength to protect sperm from damage by shear forces encountered during epididymal transit or ejaculation (449). It was reported that outer dense fibers are antigenically similar to actin (403) and that an ATPase is associated with the outer dense fibers (450,452). However, biochemical studies have not found a similarity in composition of outer dense fibers to actin, myosin, or tubulin (404). Other investigators have been unable to detect ATPase activity associated with outer dense fibers (406).

Their ATPase activity (362) generates force unidirectionally towards the minus (–) end of microtubules to generate sliding forces between adjacent doublets of microtubules during flagellar movement (363). Dyneins consist of heavy, intermediate, light intermediate, and light chains. The motor activity is associated with heavy chains and axonemal dyneins are present as heterotrimers, heterodimers and monomers of heavy chains (364). Most of what is known about the function of axonemal dyneins comes from studies on ciliated unicellular organisms (365) and sea urchin sperm (362,363) and is presumed to apply to mammalian sperm.

Other proteins associated with the perinuclear theca include actin, spectrin, and calmodulin (219,220). In addition, antibodies have localized several proteins to the perinuclear theca, but they remain to be identified or characterized using molecular methods. These include the thecins (221), the Dp71f isoform of dystrophin, β-dystrobrevins (222), and antigen AJ-p90 (223). Roles of the Sperm Head Cytoskeleton Sperm-head cytoskeletal components have a structural role in defining the shape of the sperm head (188,189), and a functional role in aiding sperm penetration of the egg and its investments at fertilization (201,224).

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Knobil and Neill's Physiology of Reproduction, Volume 1-2, Third Edition by Paul Wassarman, Jimmy D. Neill


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