Essentials of Human Physiology for Pharmacy (Plant - download pdf or read online

By Laurie Kelly McCorry

ISBN-10: 1566769973

ISBN-13: 9781566769976

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Antipsychotic drugs, such as Thorazine® (chlorpromazine) and Haldol® (haloperidol), minimize symptoms of schizophrenia by blocking dopamine receptors and thus preventing excess dopamine from exerting its effects. An agonist is a drug that binds to a given receptor and stimulates it.

1). 1 Distinguishing Features of Graded Potentials and Action Potentials Graded potentials Action potentials Short-distance signals Long-distance signals Magnitude is stimulus dependent Magnitude is constant (all-or-none phenomenon) Signal travels by local current flow Signal travels by local current flow or by saltatory conduction Magnitude of signal dissipates as it moves away from the site of stimulation Magnitude of signal is maintained along entire length of neuron Initiated at synapses (where one neuron comes into contract with another) Initiated at axon hillock Result in depolarization or hyperpolarization Depolarization only Membrane Potential (mv) comes into contact with another neuron.

Eventually, the initial force moving Na+ ions inward down their concentration gradient is exactly balanced by the subsequent force moving Na+ ions outward down their electrical gradient, so there is no further net diffusion of sodium. The membrane potential at this point has reached the equilibrium potential for Na+ (ENa+) and is equal to +60 mV. Therefore, when the permeability of the plasma membrane to sodium is high compared to that of potassium, the membrane potential approaches +60 mV. At any given time, the membrane potential is closer to the equilibrium potential of the more permeable ion.

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Essentials of Human Physiology for Pharmacy (Plant Engineering Series) by Laurie Kelly McCorry

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