By Chris A. Liacouras, Jonathan E. Markowitz
This quantity offers a historical past of Eosinophilic Esophagitis (EoE), a easy figuring out of the body structure of the eosinophil, and a present figuring out of the pathophysiology and genetics of EoE. The emphasis is on medical functions together with providing indicators, analysis and therapies for sufferers with EoE. Written by means of either pediatric and grownup specialists within the fields of gastroenterology, hypersensitivity and pathology, this quantity contains the hottest details. offering functional details worthy within the therapy of sufferers, this ebook should be of serious worth to gastroenterologists, allergists, pathologists, scientific citizens, fellows, internists, and normal practitioners who deal with sufferers with eosinophilic esophagitis.
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Extra info for Eosinophilic Esophagitis (Clinical Gastroenterology)
Dissociation between symptoms and histological severity in pediatric eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2009;48(2):152–60. 23. Gupta SK, Fitzgerald JF, Chong SK, Crofﬁe JM, Collins MH. Vertical lines in distal esophageal mucosa (VLEM): a true endoscopic manifestation of esophagitis in children? Gastrointest Endosc. 1997;45(6):485–9. 24. Orenstein SR, Shalaby TM, Di Lorenzo C, et al. The spectrum of pediatric eosinophilic esophagitis beyond infancy: a clinical series of 30 children.
J Clin Invest. 2006;116(2):536–47. 9. Protheroe C, Woodruff SA, de Petris G, et al. A novel histologic scoring system to evaluate mucosal biopsies from patients with eosinophilic esophagitis. Clin Gastroenterol Hepatol. 2009;7(7):749–55,e711. 10. Furuta GT, Liacouras CA, Collins MH, et al. Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment. Gastroenterology. 2007;133(4):1342–63. 11. Noel RJ, Putnam PE, Rothenberg ME. Eosinophilic esophagitis.
Taken together, these data strongly support a contribution, if not the core cause for EoE, from airborne allergens. However, these data do cannot establish a causal mechanism for the role of airborne allergens in human EoE to a similar degree as that of amino acid-based formulas for dietary allergens . These data suggest that EoE may point to a larger “allergy epidemic” and may not be a disease limited to the gastrointestinal tract. This topic is addressed in the consensus recommendations that patients with EoE receive comprehensive evaluation and management of atopic disease .
Eosinophilic Esophagitis (Clinical Gastroenterology) by Chris A. Liacouras, Jonathan E. Markowitz