Read e-book online Drugs in Pregnancy and Lactation PDF

By Gerald G. Briggs, Roger K. Freeman, Sumner J. Yaffe

ISBN-10: 0781732034

ISBN-13: 9780781732031

The completely up-to-date 6th version of this well known reference presents sensible, trustworthy details on greater than 1,000 prescribed drugs and common items that could be utilized by pregnant girls or lactating moms. greater than two hundred drugs--including nicotine, thalidomide, and new anesthetics--are extra to this version. Chapters on 2 hundred medicinal drugs, together with cocaine, benzodiazepines, and hormonal items, are considerably revised. every one drug monograph contains a possibility issue ranking that shows the substance's capability for adversarial results within the fetus or toddler. medicinal drugs are indexed alphabetically and listed by means of either alternate and customary names in order that the reader can quick locate details.

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Clin Obstet Gynecol 1990;33:276–89. 8. de Martino M, Tovo P-A, Pezzotti P, Galli L, Massironi E, Ruga E, Floreea F, Plebani A, Gabiano C, Zuccotti GV. HIV-1 transmission through breast-milk: appraisal of risk according to duration of feeding. AIDS 1992;6:991–7. 9. Van de Perre P. Postnatal transmission of human immunodeficiency virus type 1: the breast feeding dilemma. Am J Obstet Gynecol 1995;173:483–7. Index ACARBOSE Drugs in Pregnancy and Lactation Name: ACARBOSE Class: Antidiabetic Risk Factor: BM Fetal Risk Summary Breast Feeding Summary References Fetal Risk Summary Acarbose is an oral a-glucosidase inhibitor that delays the digestion of ingested carbohydrates within the gastrointestinal tract, thereby reducing the rise in blood glucose after meals (1).

The mother was treated for progressive liver failure and eventually recovered. The Rocky Mountain Poison and Drug Center reported the results of a nationwide study on acetaminophen overdose during pregnancy involving 113 women (13). Of the 60 cases that had appropriate laboratory and pregnancy outcome data, 19 occurred during the 1st trimester, 22 during the 2nd trimester, and 19 during the 3rd trimester. In those cases with a potentially toxic serum level of acetaminophen, early treatment with N-acetylcysteine was statistically associated with an improved pregnancy outcome by lessening the incidence of spontaneous abortion and fetal death.

Because the prolonged elimination would increase the teratogenic potential for women of childbearing age (see also Etretinate), the manufacturer states that alcohol must not be ingested during therapy with acitretin and for 2 months after cessation of therapy because of the long elimination period of acitretin (1). In a 1994 reference, the concentrations of etretinate, acitretin, and 13-cis-acitretin were measured in plasma and subcutaneous fat samples from 37 women of childbearing age (2). Twenty of the women were receiving acitretin and 17 had stopped.

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Drugs in Pregnancy and Lactation by Gerald G. Briggs, Roger K. Freeman, Sumner J. Yaffe


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