Read e-book online Berne and Levy Physiology: with STUDENT CONSULT Online PDF

By Robert M. Berne MD, Bruce A. Stanton PhD

ISBN-10: 0323045820

ISBN-13: 9780323045827

Lengthy revered for its scientifically rigorous method, this best-selling textual content now comprises significant updates to deliver you the entire most up-to-date wisdom within the box. Honed and shortened to stress the center info wanted by way of scholars of body structure this day, it additionally encompasses a new full-color layout and all-new full-color art to augment clarity and increase your comprehension of each idea. With entry to the complete contents on-line at pupil seek advice, this wide-spread e-book offers an in-depth realizing of body structure extra powerfully and successfully than ever before.

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Read or Download Berne and Levy Physiology: with STUDENT CONSULT Online Access, 6e PDF

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Example text

As illustrated in Figure 1-10, the magnitude of the osmotic pressure generated by a solution of protein does not conform to van't Hoff's law. The cause of this anomalous relationship between protein concentration and osmotic pressure is not completely understood but appears to be related to the size and shape of the protein molecule. For example, the correlation to van't Hoff's law is more precise with small, globular proteins than with larger protein molecules. The oncotic pressure exerted by proteins in human plasma has a normal value of approximately 26 to 28 mm Hg.

The protein is covalently attached to a lipid molecule, which is then embedded in one leaflet of the bilayer. The glycolipid GPI anchors proteins to the outer leaflet of the membrane. , farnesyl or geranylgeranyl). Peripheral proteins may associate with the polar head groups of the membrane lipids but more commonly bind to integral or lipid-anchored proteins. Peripheral proteins are easily removed from the membrane, whereas integral and lipid-anchored proteins require the use of detergents to isolate them from the membrane.

The electrochemical gradient for any molecule (Δμx) is calculated as where R = gas constant T = temperature in degrees Kelvin ln = natural logarithm 39 / 1341 Berne and Levy Physiology, 6th Edition 40 / 1341 [X]i = concentration of X inside the cell [X]o = concentration of X outside the cell zx = valence of charged molecules F = Faraday constant Vm = membrane potential page 13 page 14 Figure 1-7 Electrochemical gradients and cellular transport of molecules. A, Because glucose is uncharged, the electrochemical gradient is determined solely by the concentration gradient for glucose across the cell membrane.

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Berne and Levy Physiology: with STUDENT CONSULT Online Access, 6e by Robert M. Berne MD, Bruce A. Stanton PhD


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